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T cell receptor usage and epitope specificity amongst CD8+ and CD4+ SARS-CoV-2-specific T cells

IntroductionThe coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has highlighted the critical importance of understanding protective long-lasting immune responses. This study investigates the epitope specificity, T cell receptor (T...

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Furkejuvvon:
Váldodahkkit: Ulrik Fahnøe, Shan Feng, Alexander P. Underwood, Kivin Jacobsen, Amir Ameri, Thomas H. Blicher, Christina S. Sølund, Brad R. Rosenberg, Liselotte Brix, Nina Weis, Jens Bukh
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: Frontiers Media S.A. 2025-02-01
Ráidu:Frontiers in Immunology
Fáttát:
SARS-CoV-2
COVID-19
T cells
flow cytometry
single-cell RNA sequencing
transcriptomics
Liŋkkat:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1510436/full
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