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THAP9 Transposase Cleaves DNA via Conserved Acidic Residues in an RNaseH-Like Domain

The catalytic domain of most ‘cut and paste’ DNA transposases have the canonical RNase-H fold, which is also shared by other polynucleotidyl transferases such as the retroviral integrases and the RAG1 subunit of V(D)J recombinase. The RNase-H fold is a mixture of beta sheets and alpha helices with t...

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Autori principali: Vasudha Sharma, Prachi Thakore, Sharmistha Majumdar
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI AG 2021-05-01
Serie:Cells
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Accesso online:https://www.mdpi.com/2073-4409/10/6/1351
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