THAP9 Transposase Cleaves DNA via Conserved Acidic Residues in an RNaseH-Like Domain
The catalytic domain of most ‘cut and paste’ DNA transposases have the canonical RNase-H fold, which is also shared by other polynucleotidyl transferases such as the retroviral integrases and the RAG1 subunit of V(D)J recombinase. The RNase-H fold is a mixture of beta sheets and alpha helices with t...
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| Principais autores: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
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MDPI AG
2021-05-01
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| Serier: | Cells |
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| Online adgang: | https://www.mdpi.com/2073-4409/10/6/1351 |
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