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Traffic-related air pollution significantly aggravates the detrimental effect of infections on the risk of Alzheimer’s disease and other dementias, especially in non-carriers of APOE4

Alzheimer’s disease (AD) is a complex neurodegenerative disorder influenced by various factors, including genetic and exposure-related. Certain combinations of these factors may promote AD more substantially than others. APOE4 is the strongest genetic risk factor for AD. Traffic-related air pollutio...

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Principais autores: Vladimir A. Popov, Svetlana Ukraintseva, Hongzhe Duan, Arseniy Yashkin, Julia Kravchenko, Igor Akushevich, Heather Whitson, Konstantin G. Arbeev, Anatoliy I. Yashin
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2026-01-01
coleção:Frontiers in Dementia
Assuntos:
aging
air pollution
Alzheimer’s disease
APOE4
dementia
infections
Acesso em linha:https://www.frontiersin.org/articles/10.3389/frdem.2025.1668381/full
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