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Development of LAG-3/FGL1 blocking peptide and combination with radiotherapy for cancer immunotherapy

Aside from antibodies, peptides show great potential as immune checkpoint inhibitors (ICIs) due to several advantages, such as better tumor penetration and lower cost. Lymphocyte-activation gene 3 (LAG-3) is an immune checkpoint which can induce T cell dysfunction through interaction with its solubl...

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Збережено в:
Автори: Yuzhen Qian, Yixuan Sun, Peishang Shi, Xiuman Zhou, Qiongqiong Zhang, Qingyu Dong, Shengzhe Jin, Lu Qiu, Xiaoshuang Niu, Xiaowen Zhou, Wenshan Zhao, Yahong Wu, Wenjie Zhai, Yanfeng Gao
Формат: Artigo
Мова:Inglês
Опубліковано: Elsevier 2024-03-01
Серія:Acta Pharmaceutica Sinica B
Предмети:
LAG-3
FGL1
PD-1
PD-L1
Peptide
Immune checkpoint
Онлайн доступ:http://www.sciencedirect.com/science/article/pii/S221138352300480X
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