Exploring the Anti-Influenza Activity of <i>closo</i>-Borate Platforms: Structure–Activity Relationship of Amino Acid-Functionalized <i>closo</i>-Dodecaborate Derivatives Against Influenza Virus A/Cheboksary/125/2020 (H1N1)pdm09

The emergence of drug-resistant influenza virus strains necessitates the development of novel antiviral agents with unique mechanisms of action. This study presents the synthesis and in vitro evaluation of a new class of antiviral compounds: sodium salts of amino acid ester conjugates based on the <...

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Main Authors:	Timur M. Garaev, Ilya I. Yudin, Natalya V. Breslav, Tatyana V. Grebennikova, Evgenii Yu. Matveev, Elizaveta A. Eshtukova-Shcheglova, Ilya E. Sokolov, Varvara V. Avdeeva, Konstantin Yu. Zhizhin, Nikolai T. Kuznetsov
Format:	Artigo
Language:	Inglês
Published:	MDPI AG 2025-10-01
Series:	Molecules
Subjects:	antiviral activity viroporins amino acids polyhedral boron anions <i>closo</i>-dodecaborate anion tetrahydropyran
Online Access:	https://www.mdpi.com/1420-3049/30/21/4225
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