Analogues of Natural Chalcones as Efficient Inhibitors of AKR1C3

Naturally occurring substances are valuable resources for drug development. In this respect, chalcones are known to be antiproliferative agents against prostate cancer cell lines through various mechanisms or targets. Based on the literature and preliminary results, we aimed to study and optimise th...

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Principais autores:	Gabriele Möller, Veronika Temml, Antonio Cala Peralta, Océane Gruet, Pascal Richomme, Denis Séraphin, Guillaume Viault, Luisa Kraus, Petra Huber-Cantonati, Elisabeth Schopfhauser, Johanna Pachmayr, Janina Tokarz, Daniela Schuster, Jean-Jacques Helesbeux, Kenneth Allen Dyar
格式:	Artigo
语言:	Inglês
出版:	MDPI AG 2022-01-01
丛编:	Metabolites
主题:	chalcone aldo-keto reductase cancer AKR1C3 17β-hydroxysteroid dehydrogenase 3α-hydroxysteroid dehydrogenase
在线阅读:	https://www.mdpi.com/2218-1989/12/2/99
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