Heparin-binding EGF-like growth factor: mechanisms of biological activity and potential therapeutic applications

The diphtheria toxin receptor on sensitive mammalian cells is known as the membrane anchored precursor of heparin-binding EGF-like growth factor (HB-EGF). When the precursor is cleaved by metalloproteinases, a soluble form (sHB-EGF) is formed that can bind to the EGF receptors, resulting in activati...

Descripció completa

Dades bibliogràfiques

Autors principals:	L. M. Dronko, T. M. Lutsenko, N. V. Korotkevych, I. O. Vovk, D. A. Zhukova, S. I. Romaniuk, A. A. Siromolot, A. J. Labyntsev, D. V. Kolybo
Format:	Artigo
Idioma:	Inglês
Publicat:	National Academy of Sciences of Ukraine, Palladin Institute of Biochemistry 2024-10-01
Col·lecció:	The Ukrainian Biochemical Journal
Matèries:	cell proliferation diphtheria toxin egf receptor heparin-binding egf-like growth factor signal transduction wound healing
Accés en línia:	http://ukrbiochemjournal.org/wp-content/uploads/2024/10/Dronko_96_5.pdf
Etiquetes:	Afegir etiqueta Sense etiquetes, Sigues el primer a etiquetar aquest registre!