Integrative phosphoproteomic analysis reveals co-regulatory phosphorylation networks of rhotekin in cancer progression

Abstract Rhotekin (RTKN), a Rho GTPase effector, promotes the development of malignancies, including breast, gastric, and colon cancers, by enhancing cell proliferation and migration while inhibiting apoptosis. Despite its oncogenic role, the phosphoregulatory network of RTKN remains largely unexplo...

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Detalhes bibliográficos

Principais autores:	Akhina Palollathil, Althaf Mahin, Athira Perunelly Gopalakrishnan, Alimath Sambreena, Samseera Ummar, Prathik Basthikoppa Shivamurthy, R. Ganesan, Manavalan Vijayakumar, Rajesh Raju
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Springer 2026-04-01
Colecção:	Discover Oncology
Assuntos:	Post-translational modifications Cancer Nervous system Phosphorylation Mass spectrometry Phosphoproteomics
Acesso em linha:	https://doi.org/10.1007/s12672-026-04982-6
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