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Actin-dependent activation of serum response factor in T cells by the viral oncoprotein tip

<p>Abstract</p> <p>Serum response factor (SRF) acts as a multifunctional transcription factor regulated by mutually exclusive interactions with ternary complex factors (TCFs) or myocardin-related transcription factors (MRTFs). Binding of Rho- and actin-regulated MRTF:SRF complexes to target gene pro...

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Principais autores: Katsch Kristin, de Jong Sarah, Albrecht Jens-Christian, Steger Julia, Genth Harald, Posern Guido, Biesinger Brigitte
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2012-03-01
coleção:Cell Communication and Signaling
Assuntos:
Actin
Herpesvirus saimiri
Lck
MRTF
Oncoprotein
Serum response factor
T lymphocyte
Acesso em linha:http://www.biosignaling.com/content/10/1/5
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