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Actin-dependent activation of serum response factor in T cells by the viral oncoprotein tip

<p>Abstract</p> <p>Serum response factor (SRF) acts as a multifunctional transcription factor regulated by mutually exclusive interactions with ternary complex factors (TCFs) or myocardin-related transcription factors (MRTFs). Binding of Rho- and actin-regulated MRTF:SRF complexes to target gene pro...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Katsch Kristin, de Jong Sarah, Albrecht Jens-Christian, Steger Julia, Genth Harald, Posern Guido, Biesinger Brigitte
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2012-03-01
Schriftenreihe:Cell Communication and Signaling
Schlagworte:
Actin
Herpesvirus saimiri
Lck
MRTF
Oncoprotein
Serum response factor
T lymphocyte
Online-Zugang:http://www.biosignaling.com/content/10/1/5
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