Modulation of mTOR signaling as a strategy for the treatment of Pompe disease
Abstract Mechanistic target of rapamycin (mTOR) coordinates biosynthetic and catabolic processes in response to multiple extracellular and intracellular signals including growth factors and nutrients. This serine/threonine kinase has long been known as a critical regulator of muscle mass. The recent...
Guardado en:
| Autores principales: | , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Springer Nature
2017-01-01
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| Colección: | EMBO Molecular Medicine |
| Materias: | |
| Acceso en línea: | https://doi.org/10.15252/emmm.201606547 |
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