Hemagglutinin Subtype Specificity and Mechanisms of Highly Pathogenic Avian Influenza Virus Genesis

Highly Pathogenic Avian Influenza Viruses (HPAIVs) arise from low pathogenic precursors following spillover from wild waterfowl into poultry populations. The main virulence determinant of HPAIVs is the presence of a multi-basic cleavage site (MBCS) in the hemagglutinin (HA) glycoprotein. The MBCS al...

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Detaylı Bibliyografya
Asıl Yazarlar:	Anja C. M. de Bruin, Mathis Funk, Monique I. Spronken, Alexander P. Gultyaev, Ron A. M. Fouchier, Mathilde Richard
Materyal Türü:	Artigo
Dil:	Inglês
Baskı/Yayın Bilgisi:	MDPI AG 2022-07-01
Seri Bilgileri:	Viruses
Konular:	Highly Pathogenic Avian Influenza Viruses Low-Pathogenic Avian Influenza Viruses multibasic cleavage site virulence pathogen evolution proteolytic cleavage
Online Erişim:	https://www.mdpi.com/1999-4915/14/7/1566
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Hemagglutinin Subtype Specificity and Mechanisms of Highly Pathogenic Avian Influenza Virus Genesis

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