Structure-activity relationship study of steroidal 1,2,4,5-tetraoxane animalarials using computational procedures

A three-dimensional QSAR pharmacophore model for antimalarial activity of steroidal 1,2,4,5-tetraoxanes was developed from a set of 17 substituted antimalarial derivatives out of 27 analogues that exhibited remarkable in vitro activity (below 100 ng/mL) against sensitive and multidrug-resistant Plas...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Bhattacharjee Apurba K., Carvalho Keith A., Opsenica Dejan M., Šolaja Bogdan A.
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Serbian Chemical Society 2005-01-01
Цуврал:	Journal of the Serbian Chemical Society
Нөхцлүүд:	qsar 3d pharmacophore tetraoxane malaria steroids
Онлайн хандалт:	http://www.doiserbia.nb.rs/img/doi/0352-5139/2005/0352-51390503329B.pdf
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!