Structure-activity relationship study of steroidal 1,2,4,5-tetraoxane animalarials using computational procedures
A three-dimensional QSAR pharmacophore model for antimalarial activity of steroidal 1,2,4,5-tetraoxanes was developed from a set of 17 substituted antimalarial derivatives out of 27 analogues that exhibited remarkable in vitro activity (below 100 ng/mL) against sensitive and multidrug-resistant Plas...
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| Principais autores: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Serbian Chemical Society
2005-01-01
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| Serier: | Journal of the Serbian Chemical Society |
| Fag: | |
| Online adgang: | http://www.doiserbia.nb.rs/img/doi/0352-5139/2005/0352-51390503329B.pdf |
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