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Simultaneous Analysis of the p16 Gene and Protein in Canine Lymphoma Cells and Their Correlation with pRb Phosphorylation

Cyclin-dependent kinase inhibitor p16 (CDKN2A) primarily functions as a negative regulator of the retinoblastoma protein (pRb) pathway to prevent pRb phosphorylation, thus playing a critical role in cell cycle arrest. In canine lymphoma cells, methylation due to inactivation of the p16 gene has been...

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Bibliografische gegevens
Hoofdauteurs: Leni Maylina, Satoshi Kambayashi, Kenji Baba, Masaru Okuda
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI AG 2022-07-01
Reeks:Veterinary Sciences
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Online toegang:https://www.mdpi.com/2306-7381/9/8/393
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