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PARP7 as a new target for activating anti-tumor immunity in cancer

Abstract ADP-ribosyl transferases (ARTs) are a family of enzymes which catalyze the addition of a chain (PARylation) or a single moiety (MARylation) of ADP-ribose to their substrates. PARP7 is a mono-ADP-ribosyl transferase (mono-ART) which has recently gained attention due to its emerging role as a...

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Hlavní autoři: Katerina Popova, Johannes Benedum, Magdalena Engl, Carola Lütgendorf-Caucig, Piero Fossati, Joachim Widder, Klaus Podar, Dea Slade
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer Nature 2025-03-01
Edice:EMBO Molecular Medicine
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On-line přístup:https://doi.org/10.1038/s44321-025-00214-6
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