Protective roles of adiponectin and molecular signatures of HNF4α and PPARα as downstream targets of adiponectin in pancreatic β cells

The disease progression of the metabolic syndrome is associated with prolonged hyperlipidemia and insulin resistance, eventually giving rise to impaired insulin secretion, often concomitant with hypoadiponectinemia. As an adipose tissue derived hormone, adiponectin is beneficial for insulin secretio...

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Detalhes bibliográficos

Principais autores:	Toshiharu Onodera, Dae-Seok Kim, Risheng Ye, May-Yun Wang, Shiuhwei Chen, Bianca C. Field, Leon Straub, Xue-Nan Sun, Chao Li, Charlotte Lee, Megan Paredes, Clair Crewe, Shangang Zhao, Christine M. Kusminski, Ruth Gordillo, Philipp E. Scherer
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2023-12-01
coleção:	Molecular Metabolism
Assuntos:	Adiponectin PPARα HNF4α β cell
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2212877823001552
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