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HNF4α isoforms: the fraternal twin master regulators of liver function

In the more than 30 years since the purification and cloning of Hepatocyte Nuclear Factor 4 (HNF4α), considerable insight into its role in liver function has been gleaned from its target genes and mouse experiments. HNF4α plays a key role in lipid and glucose metabolism and intersects with not just...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Sarah H. Radi, Kiranmayi Vemuri, Jose Martinez-Lomeli, Frances M. Sladek
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2023-08-01
Schriftenreihe:Frontiers in Endocrinology
Schlagworte:
Online-Zugang:https://www.frontiersin.org/articles/10.3389/fendo.2023.1226173/full
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