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Flow cytometric analysis identifies changes in S and M phases as novel cell cycle alterations induced by the splicing inhibitor isoginkgetin.

The spliceosome is a large ribonucleoprotein complex that catalyzes the removal of introns from RNA polymerase II-transcribed RNAs. Spliceosome assembly occurs in a stepwise manner through specific intermediates referred to as pre-spliceosome complexes E, A, B, B* and C. It has been reported that sm...

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Библиографические подробности
Главные авторы: Erin J Vanzyl, Kayleigh R C Rick, Alex B Blackmore, Erin M MacFarlane, Bruce C McKay
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science (PLoS) 2018-01-01
Серии:PLoS ONE
Online-ссылка:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0191178&type=printable
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