Ezetimibe blocks the internalization of NPC1L1 and cholesterol in mouse small intestine

The multiple transmembrane protein Niemann-Pick C1 like1 (NPC1L1) is essential for intestinal cholesterol absorption. Ezetimibe binds to NPC1L1 and is a clinically used cholesterol absorption inhibitor. Recent studies in cultured cells have shown that NPC1L1 mediates cholesterol uptake through vesic...

पूर्ण विवरण

ग्रंथसूची विवरण

मुख्य लेखकों:	Chang Xie 谢畅, Zhang-Sen Zhou 周章森, Na Li 李钠, Yan Bian 卞艳, Yong-Jian Wang 王永建, Li-Juan Wang 王丽娟, Bo-Liang Li 李伯良, Bao-Liang Song 宋保亮
स्वरूप:	Artigo
भाषा:	Inglês
प्रकाशित:	Elsevier 2012-10-01
श्रृंखला:	Journal of Lipid Research
विषय:	Niemann-Pick C1 like1 cholesterol absorption endocytosis transport
ऑनलाइन पहुंच:	http://www.sciencedirect.com/science/article/pii/S0022227520431864
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