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Prenatal PM2.5 exposure impairs hippocampal synaptic development in offspring via KDM5A-mediated epigenetic derepression of Pin1

Exposure to fine particulate matter (PM2.5) has been increasingly associated with neurodevelopmental disorders, yet the underlying molecular mechanisms remain poorly defined. KDM5A, a histone lysine demethylase implicated in cognitive regulation, has not been thoroughly investigated in the context o...

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Bibliografiske detaljer
Principais autores: Chao Song, Li Zhou, Siqi Wang, Wenke Nie, Hang Yu, E. Lv, Yongping Liu, Lu Sun, Wanwei Li, Dan Li, Li Yu
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2025-11-01
Serier:Ecotoxicology and Environmental Safety
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Online adgang:http://www.sciencedirect.com/science/article/pii/S0147651325017361
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