The Role of Chaperone-Mediated Autophagy in Tissue Homeostasis and Disease Pathogenesis
Chaperone-mediated autophagy (CMA) is a selective proteolytic pathway in the lysosomes. Proteins are recognized one by one through the detection of a KFERQ motif or, at least, a KFERQ-like motif, by a heat shock cognate protein 70 (Hsc70), a molecular chaperone. CMA substrates are recognized and del...
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| Principais autores: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI AG
2024-01-01
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| coleção: | Biomedicines |
| Assuntos: | |
| Acesso em linha: | https://www.mdpi.com/2227-9059/12/2/257 |
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