The Role of Chaperone-Mediated Autophagy in Tissue Homeostasis and Disease Pathogenesis
Chaperone-mediated autophagy (CMA) is a selective proteolytic pathway in the lysosomes. Proteins are recognized one by one through the detection of a KFERQ motif or, at least, a KFERQ-like motif, by a heat shock cognate protein 70 (Hsc70), a molecular chaperone. CMA substrates are recognized and del...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
MDPI AG
2024-01-01
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| Серии: | Biomedicines |
| Предметы: | |
| Online-ссылка: | https://www.mdpi.com/2227-9059/12/2/257 |
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