Unfolded protein response in bronchopulmonary dysplasia: mechanisms, pathways, and therapeutic implications

Bronchopulmonary dysplasia (BPD) is a prevalent chronic lung disease in preterm infants, characterized by impaired alveolarization and abnormal vascular development. Growing evidence indicates that endoplasmic reticulum stress (ERS) and the unfolded protein response (UPR) are closely involved in the...

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Principais autores:	Haiyue Yu, Yongjing Guo, Xin Wang, Wanxu Guo, Yunfeng Zhang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2026-04-01
coleção:	Frontiers in Cell and Developmental Biology
Assuntos:	bronchopulmonary dysplasia endoplasmic reticulum stress hyperoxia lung development neonatal lung injury oxidative stress
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fcell.2026.1700811/full
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