Unfolded protein response in bronchopulmonary dysplasia: mechanisms, pathways, and therapeutic implications

Bronchopulmonary dysplasia (BPD) is a prevalent chronic lung disease in preterm infants, characterized by impaired alveolarization and abnormal vascular development. Growing evidence indicates that endoplasmic reticulum stress (ERS) and the unfolded protein response (UPR) are closely involved in the...

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Auteurs principaux:	Haiyue Yu, Yongjing Guo, Xin Wang, Wanxu Guo, Yunfeng Zhang
Format:	Artigo
Langue:	Inglês
Publié:	Frontiers Media S.A. 2026-04-01
Collection:	Frontiers in Cell and Developmental Biology
Sujets:	bronchopulmonary dysplasia endoplasmic reticulum stress hyperoxia lung development neonatal lung injury oxidative stress
Accès en ligne:	https://www.frontiersin.org/articles/10.3389/fcell.2026.1700811/full
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