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DGKζ in Glycerophospholipid Metabolism Regulates the DAG and PA Balance and Interacts With PTEN to Alleviate Brain Damage in Septic Mice With Hydrogen Inhalation: A Comparative Metabolomic and Phosphoproteomic Analysis

ABSTRACT Objectives: Therapeutic effects of hydrogen (H2) on sepsis‐associated encephalopathy (SAE), a severe neuroinflammatory disease, have been reported, but the underlying mechanism remains unclear. Metabolomic and phosphoproteomic analyses were utilized to explore the therapeutic mechanism of H...

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Principais autores: Yuanyuan Bai, Zeyu Li, Donglai Yan, Yi Jiang, Beibei Dong, Yonghao Yu
Format: Artigo
Jezik:Inglês
Izdano: Wiley 2025-08-01
Serija:Brain and Behavior
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Online dostop:https://doi.org/10.1002/brb3.70761
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