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4E Interacting Protein as a Potential Novel Drug Target for Nucleoside Analogues in <i>Trypanosoma brucei</i>

Human African trypanosomiasis is a neglected parasitic disease for which the current treatment options are quite limited. Trypanosomes are not able to synthesize purines de novo and thus solely depend on purine salvage from the host environment. This characteristic makes players of the purine salvag...

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Kaydedildi:
Asıl Yazarlar: Dorien Mabille, Camila Cardoso Santos, Rik Hendrickx, Mathieu Claes, Peter Takac, Christine Clayton, Sarah Hendrickx, Fabian Hulpia, Louis Maes, Serge Van Calenbergh, Guy Caljon
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MDPI AG 2021-04-01
Seri Bilgileri:Microorganisms
Konular:
trypanosomiasis
nucleoside analogues
RNAi
drug target
4E-interacting protein
Online Erişim:https://www.mdpi.com/2076-2607/9/4/826
Etiketler: Etiketle
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