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Quinolones: Mechanism, Lethality and Their Contributions to Antibiotic Resistance

Fluoroquinolones (FQs) are arguably among the most successful antibiotics of recent times. They have enjoyed over 30 years of clinical usage and become essential tools in the armoury of clinical treatments. FQs target the bacterial enzymes DNA gyrase and DNA topoisomerase IV, where they stabilise a...

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Principais autores: Natassja G. Bush, Isabel Diez-Santos, Lauren R. Abbott, Anthony Maxwell
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2020-12-01
Colecção:Molecules
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Acesso em linha:https://www.mdpi.com/1420-3049/25/23/5662
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