Antihyperalgesic Activity of Propoxazepam in the Oxaliplatin-Induced Cold Allodynia in Rats

Background. Oxaliplatin (OXP), a third-generation chemotherapeutic platinum compound, is widely used in treating metastatic colorectal cancer. However, its clinical utility is limited by oxaliplatin-induced peripheral neuropathy (OIPN), a dose-dependent and often persistent adverse effect character...

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Hlavní autoři:	Vitalii Larionov, Mykola Golovenko, Iryna Valivodz', Anatoliy Reder
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Igor Sikorsky Kyiv Polytechnic Institute 2025-11-01
Edice:	Innovative Biosystems and Bioengineering
Témata:	oxaliplatin-induced peripheral neuropathy chemotherapy-induced neuropathic pain propoxazepam allodynia GABAergic modulation anti-inflammatory action
On-line přístup:	https://ibb.kpi.ua/article/view/334984
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!