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METABOLIC PROFILE AND MECHANISMS OF GABA-TARGETED RECEPTOR PROPOXAZEPAM METABOLIZATION IN HUMAN HEPATOCYTES

The aim of this study was to identify the Propoxazepam metabolites, formed by suspension of cryopreserved human hepatocytes, using the precise method of mass LC-MS/MS analysis. Methods. A suitable chromatographic method was developed for the profiling of Propoxazepam and its metabolites. Samples...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: M. Golovenko, A. Reder, V. Larionov, S. Andronati
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences of Ukraine, Palladin Institute of Biochemistry 2022-02-01
Cyfres:Biotechnologia Acta
Pynciau:
Mynediad Ar-lein:http://biotechnology.kiev.ua/images/1_2022/golovenko_1_2022.pdf
Tagiau: Ychwanegu Tag
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