Bovine delta papillomavirus E5 oncoprotein negatively regulates the cGAS-STING signaling pathway in cattle in a spontaneous model of viral disease

Persistent infection and tumorigenesis by papillomaviruses (PVs) require viral manipulation of various cellular processes, including those involved in innate immune responses. The cyclic guanosine monophosphate-adenosine monophosphate synthase-stimulator of interferon genes (cGAS-STING) pathway has...

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Bibliographic Details

Main Authors:	Francesca De Falco, Anna Cutarelli, Adriana Florinela Catoi, Barbara Degli Uberti, Bianca Cuccaro, Sante Roperto
Format:	Artigo
Language:	Inglês
Published:	Frontiers Media S.A. 2022-10-01
Series:	Frontiers in Immunology
Subjects:	bovine papillomavirus E5 oncoprotein cGAS stimulator of interferon genes (STING) IKK kinase complex transcription factor IRFs ELKS
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2022.937736/full
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