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LRP1 facilitates Jamestown Canyon virus infection of neurons

ABSTRACT Jamestown Canyon virus (JCV) is a bunyavirus and arbovirus that causes viral neuroinvasive disease in North America. JCV neuropathogenesis is understudied, and no pro-viral host factors for cellular infection have been identified. Here, we assessed the role of low-density lipoprotein recept...

Deskribapen osoa

Gorde:
Egile Nagusiak: Zachary D. Frey, David A. Price, Kaleigh A. Connors, Rachael E. Rush, Griffin Brown, Cade E. Sterling, Farheen Fatma, Safder S. Ganaie, Xiaoxia Cui, Zachary P. Wills, Gaya K. Amarasinghe, Daisy W. Leung, Amy L. Hartman
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2025-12-01
Saila:Journal of Virology
Gaiak:
Jamestown Canyon virus
primary rat neurons
LRP1
CD91
bunyavirus
host factor
Sarrera elektronikoa:https://journals.asm.org/doi/10.1128/jvi.01841-25
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