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Dynein/Dynactin-mediated transport of kinetochore components off kinetochores and onto spindle poles induced by nordihydroguaiaretic acid.

The mitotic checkpoint functions to ensure accurate chromosome segregation by regulating the progression from metaphase to anaphase. Once the checkpoint has been satisfied, it is inactivated in order to allow the cell to proceed into anaphase and complete the cell cycle. The minus end-directed micro...

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Auteurs principaux: Jakub K Famulski, Larissa J Vos, Jerome B Rattner, Gordon K Chan
Format: Artigo
Langue:Inglês
Publié: Public Library of Science (PLoS) 2011-01-01
Collection:PLoS ONE
Accès en ligne:http://europepmc.org/articles/PMC3030593?pdf=render
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