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The mitotic spindle is required for loading of the DASH complex onto the kinetochore

A role for the mitotic spindle in the maturation of the kinetochore has not been defined previously. Here we describe the isolation of a novel and conserved essential gene, ASK1, from Saccharomyces cerevisiae involved in this process. ask1 mutants display either G(2)/M arrest or segregation of DNA m...

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Detalhes bibliográficos
Main Authors: Li, Yumei, Bachant, Jeff, Alcasabas, Annette A., Wang, Yanchang, Qin, Jun, Elledge, Stephen J.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2002
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC155319/
https://ncbi.nlm.nih.gov/pubmed/11799062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.959402
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