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cis-Regulatory Circuits Regulating NEK6 Kinase Overexpression in Transformed B Cells Are Super-Enhancer Independent

Alterations in distal regulatory elements that control gene expression underlie many diseases, including cancer. Epigenomic analyses of normal and diseased cells have produced correlative predictions for connections between dysregulated enhancers and target genes involved in pathogenesis. However, w...

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Bibliográfalaš dieđut
Váldodahkkit: Yue Huang, Olivia I. Koues, Jiang-yang Zhao, Regina Liu, Sarah C. Pyfrom, Jacqueline E. Payton, Eugene M. Oltz
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: Elsevier 2017-03-01
Ráidu:Cell Reports
Fáttát:
Liŋkkat:http://www.sciencedirect.com/science/article/pii/S221112471730284X
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