Ultrasensitive gene regulation by positive feedback loops in nucleosome modification
Abstract Eukaryotic transcription involves the synergistic interaction of many different proteins. However, the question remains how eukaryotic promoters achieve ultrasensitive or threshold responses to changes in the concentration or activity of a single transcription factor (TF). We show theoretic...
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| Principais autores: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer Nature
2008-04-01
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| Colecção: | Molecular Systems Biology |
| Assuntos: | |
| Acesso em linha: | https://doi.org/10.1038/msb.2008.21 |
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