Pleiotropic association of LIPC variants with lipid and urinary 8-hydroxy deoxyguanosine levels in a Taiwanese population

Abstract Background Hepatic lipase (HL, encoded by LIPC) is a glycoprotein primarily synthesized and secreted by hepatocytes. Previous studies had demonstrated that HL is crucial for reverse cholesterol transport and affects the metabolism, composition, and level of several lipoproteins. In current...

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Autors principals:	Ming-Sheng Teng, Semon Wu, Lung-An Hsu, I-Shiang Tzeng, Hsin-Hua Chou, Cheng-Wen Su, Yu-Lin Ko
Format:	Artigo
Idioma:	Inglês
Publicat:	BMC 2019-05-01
Col·lecció:	Lipids in Health and Disease
Matèries:	Hepatic lipase Single-nucleotide polymorphism Mediation analysis Suppression effect Triglyceride level High-density lipoprotein cholesterol level
Accés en línia:	http://link.springer.com/article/10.1186/s12944-019-1057-9
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