Pleiotropic association of LIPC variants with lipid and urinary 8-hydroxy deoxyguanosine levels in a Taiwanese population

Abstract Background Hepatic lipase (HL, encoded by LIPC) is a glycoprotein primarily synthesized and secreted by hepatocytes. Previous studies had demonstrated that HL is crucial for reverse cholesterol transport and affects the metabolism, composition, and level of several lipoproteins. In current...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Ming-Sheng Teng, Semon Wu, Lung-An Hsu, I-Shiang Tzeng, Hsin-Hua Chou, Cheng-Wen Su, Yu-Lin Ko
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	BMC 2019-05-01
Цуврал:	Lipids in Health and Disease
Нөхцлүүд:	Hepatic lipase Single-nucleotide polymorphism Mediation analysis Suppression effect Triglyceride level High-density lipoprotein cholesterol level
Онлайн хандалт:	http://link.springer.com/article/10.1186/s12944-019-1057-9
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!