The Nrf2 induction prevents ferroptosis in Friedreich's Ataxia
Ferroptosis is an iron-dependent cell death caused by impaired glutathione metabolism, lipid peroxidation and mitochondrial failure. Emerging evidences report a role for ferroptosis in Friedreich's Ataxia (FRDA), a neurodegenerative disease caused by the decreased expression of the mitochondrial pro...
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| Hlavní autoři: | , , , , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Elsevier
2021-01-01
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| Edice: | Redox Biology |
| Témata: | |
| On-line přístup: | http://www.sciencedirect.com/science/article/pii/S2213231720309964 |
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