PrecivityAD2™ Blood Test: Analytical Validation of an LC-MS/MS Assay for Quantifying Plasma Phospho-tau217 and Non-Phospho-tau217 Peptide Concentrations That Are Used with Plasma Amyloid-β42/40 in a Multianalyte Assay with Algorithmic Analysis for Detecting Brain Amyloid Pathology

Alzheimer’s disease (AD) is a progressive irreversible neurodegenerative disorder that represents a major global public health concern. Traditionally, AD is diagnosed using cerebrospinal fluid biomarker analysis or brain imaging modalities. Recently, less burdensome, more widely available blood biom...

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Principais autores:	Stephanie M. Eastwood, Matthew R. Meyer, Kristopher M. Kirmess, Traci L. Wente-Roth, Faith Irvin, Mary S. Holubasch, Philip B. Verghese, Tim West, Joel B. Braunstein, Kevin E. Yarasheski, John H. Contois
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2024-08-01
Colecção:	Diagnostics
Assuntos:	Alzheimer’s biomarker blood biomarker test diagnostic tool mass spectrometry analytical methods/validity brain amyloid plaques
Acesso em linha:	https://www.mdpi.com/2075-4418/14/16/1739
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