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Aβ‐ and tau‐associated neuroinflammatory signatures in Alzheimer's disease

Abstract INTRODUCTION Neuroinflammation is increasingly recognized as a key contributor to Alzheimer's disease (AD) progression, with distinct responses linked to amyloid beta (Aβ) and tau pathology. Two detrimental waves of neuroinflammation have been proposed, the first during early Aβ accumulatio...

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Autori principali: Bruna Bellaver, Guilherme Povala, Marco Antônio De Bastiani, Ilaria Pola, Pamela C. L. Ferreira, Guilherme Bauer‐Negrini, João Pedro Ferrari‐Souza, Douglas T. Leffa, Firoza Z. Lussier, Joseph Therriault, Nesrine Rahmouni, Jenna Stevenson, Stijn Servaes, Riddhi Patira, Serge Gauthier, Dana L. Tudorascu, Thomas K. Karikari, Nicholas Ashton, Kaj Blennow, Henrik Zetterberg, Eduardo R. Zimmer, Andrea L. Benedet, Pedro Rosa‐Neto, Tharick A. Pascoal
Natura: Artigo
Lingua:Inglês
Pubblicazione: Wiley 2026-04-01
Serie:Alzheimer’s & Dementia: Translational Research & Clinical Interventions
Soggetti:
Alzheimer's disease
biomarkers
neuroinflammation
positron emission tomography
Accesso online:https://doi.org/10.1002/trc2.70275
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