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The shear stress-induced transcription factor KLF2 affects dynamics and angiopoietin-2 content of Weibel-Palade bodies.

BACKGROUND: The shear-stress induced transcription factor KLF2 has been shown to induce an atheroprotective phenotype in endothelial cells (EC) that are exposed to prolonged laminar shear. In this study we characterized the effect of the shear stress-induced transcription factor KLF2 on regulation a...

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Principais autores: Ellen L van Agtmaal, Ruben Bierings, Bieuwke S Dragt, Thomas A Leyen, Mar Fernandez-Borja, Anton J G Horrevoets, Jan Voorberg
格式: Artigo
語言:Inglês
出版: Public Library of Science (PLoS) 2012-01-01
叢編:PLoS ONE
在線閱讀:http://europepmc.org/articles/PMC3371018?pdf=render
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