P2X7 Receptor Activation Modulates Autophagy in SOD1-G93A Mouse Microglia
Autophagy and inflammation play determinant roles in the pathogenesis of Amyotrophic Lateral Sclerosis (ALS), an adult-onset neurodegenerative disease characterized by deterioration and final loss of upper and lower motor neurons (MN) priming microglia to sustain neuroinflammation and a vicious cycl...
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| Hlavní autoři: | , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Frontiers Media S.A.
2017-08-01
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| Edice: | Frontiers in Cellular Neuroscience |
| Témata: | |
| On-line přístup: | http://journal.frontiersin.org/article/10.3389/fncel.2017.00249/full |
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