Histaminergic transmission slows progression of amyotrophic lateral sclerosis

Abstract Background Histamine is an immune modulator, neuroprotective, and remyelinating agent, beneficially acting on skeletal muscles and promoting anti‐inflammatory features in amyotrophic lateral sclerosis (ALS) microglia. Drugs potentiating the endogenous release of histamine are in trial for n...

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Autors principals:	Savina Apolloni, Susanna Amadio, Paola Fabbrizio, Giovanna Morello, Antonio Gianmaria Spampinato, Emanuele Claudio Latagliata, Illari Salvatori, Daisy Proietti, Alberto Ferri, Luca Madaro, Stefano Puglisi‐Allegra, Sebastiano Cavallaro, Cinzia Volonté
Format:	Artigo
Idioma:	Inglês
Publicat:	Wiley 2019-08-01
Col·lecció:	Journal of Cachexia, Sarcopenia and Muscle
Matèries:	ALS Histamine Motor neurons Microglia Skeletal muscles SOD1‐G93A
Accés en línia:	https://doi.org/10.1002/jcsm.12422
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