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Colony-stimulating factor 1 receptor inhibition is neuroprotective to photoreceptors in retinal detachment

Abstract Retinal detachment (RD) triggers a neuroinflammatory response aimed at clearing damaged photoreceptors (PR) and limiting injury. However, this response can unintentionally worsen retinal neurodegeneration. Retinal microglia (MG) and infiltrating monocytes (Mø) play key roles in this process...

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Principais autores: Sara Pastor-Puente, Rebecca Jung, Lucia Gonzalez-Buendia, Eleftherios I. Paschalis, Demetrios G. Vavvas, Andrius Kazlauskas, Daniel E. Maidana
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2026-02-01
Serier:Cell Death and Disease
Online adgang:https://doi.org/10.1038/s41419-026-08470-1
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