Divergence in photoreceptor cell death and neuroinflammation in transvitreal and transscleral subretinal delivery in mice

Abstract Subretinal injections provide direct access to photoreceptors and RPE, which is crucial for the delivery of gene therapy and neuroprotective approaches. To access the subretinal space, transvitreal (TV) and transscleral (TS) subretinal injections have been widely used in humans and animal m...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Daniel E. Maidana, Sara Pastor Puente, Catherine Wang, Shivam Chandra, Lucia Gonzalez-Buendia, Eleftherios Paschalis Ilios, Andrius Kazlauskas, Demetrios G. Vavvas
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	BMC 2025-02-01
Schriftenreihe:	Journal of Inflammation
Schlagworte:	Retinal detachment Outer nuclear layer CD11b CX3CR1 CCR2 Gliosis
Online-Zugang:	https://doi.org/10.1186/s12950-025-00433-1
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!