Impact of cryopreservation on CAR T production and clinical response

Adoptive cell therapy with chimeric antigen receptor (CAR) T cells has become an efficient treatment option for patients with hematological malignancies. FDA approved CAR T products are manufactured in centralized facilities from fresh or frozen leukapheresis and the cryopreserved CAR T infusion pro...

Fuld beskrivelse

Bibliografiske detaljer

Principais autores:	Karin Brezinger-Dayan, Orit Itzhaki, Jenny Melnichenko, Adva Kubi, Li-at Zeltzer, Elad Jacoby, Abraham Avigdor, Ronnie Shapira Frommer, Michal J. Besser
Format:	Artigo
Sprog:	Inglês
Udgivet:	Frontiers Media S.A. 2022-10-01
Serier:	Frontiers in Oncology
Fag:	CAR T cells cryopreservation PBMC CAR T manufacturing clinical trial
Online adgang:	https://www.frontiersin.org/articles/10.3389/fonc.2022.1024362/full
Tags:	Tilføj Tag Ingen Tags, Vær først til at tagge denne postø!