Integrated spatial multi-omics delineates fatty acid degradation fuels malignant evolution at the tumour periphery in cervical squamous cell carcinomaResearch in context

Summary: Background: Cervical squamous cell carcinoma (CSCC) exhibits profound spatial heterogeneity in evolutionary trajectories across distinct tumour foci, yet the underlying mechanisms remain poorly understood. Methods: In this study, we performed an integrated spatial transcriptomic and metabo...

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主要な著者:	Shitong Lin, Zhihui Luo, Yuting Li, Bai Hu, Minghan Qu, Binghan Liu, Canhui Cao, Ting Peng, Miaochun Xu, Yashi Xu, Xiaojie Liu, Xiaoli Wang, Li Li, Wencheng Ding, Zhenyu Xu, Ruizhi Li, Jingwei Zhao, Jingmin Zhang, Lingfang Wang, Fang Ren, Chaolong Wang, Peng Wu
フォーマット:	Artigo
言語:	Inglês
出版事項:	Elsevier 2026-05-01
シリーズ:	EBioMedicine
主題:	Spatial transcriptomics Spatial metabolomics Fatty acid degradation EMT CSCC
オンライン･アクセス:	http://www.sciencedirect.com/science/article/pii/S2352396426001386
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