Engineering Clostridial Aldehyde/Alcohol Dehydrogenase for Selective Butanol Production

ABSTRACT Butanol production by Clostridium acetobutylicum is accompanied by coproduction of acetone and ethanol, which reduces the yield of butanol and increases the production cost. Here, we report development of several clostridial aldehyde/alcohol dehydrogenase (AAD) variants showing increased bu...

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Autori principali:	Changhee Cho, Seungpyo Hong, Hyeon Gi Moon, Yu-Sin Jang, Dongsup Kim, Sang Yup Lee
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology 2019-02-01
Serie:	mBio
Soggetti:	Clostridium acetobutylicum aldehyde/alcohol dehydrogenase butanol selectivity metabolic engineering protein engineering
Accesso online:	https://journals.asm.org/doi/10.1128/mBio.02683-18
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